Out Of The Black Hole

Posts Tagged ‘Gastrointestinal’

Butterbur for Migraines

Saturday, November 28th, 2009

Migraineurs would prefer not to have migraines at all. If headache cannot be eliminated, reducing the number of migraine episodes they experience would certainly be an improvement. It would be even better if it could be done without synthetic pharmacologicals.

Migraineurs, meet butterbur (Petasites hybridus). Butterbur is a shrub native to southwestern Asia, Europe, and northern Africa. It is not what’s above ground that makes it interesting though, it’s the root. Several studies have shown that daily doses of extract of butterbur root reduced the frequency of migraine episodes by approximately 50% in almost 80% of the participants.

Butterbur is used in Europe and Asia, but only in the last decade have American doctors looked at it as a viable herbal preventative for migraineurs. Double blind, placebo-controlled studies conducted in 2000, 2002, 2003, 2004, and 2005 all confirmed the herb’s efficacy.

Migraine frequency reduction ranged from 37% – 62% among study participants, with almost no side effects. The only side effect reported was minor gastrointestinal upset, and that was in a small portion of both the herb and placebo groups. Butterbur is currently considered to be safe, as of this writing, to take with other migraine medications. A healthcare professional should always be included in the decision to add herbal products to any treatment regimen.

Crude butterbur contains pyrrolizidine alkaloids (PAs). These alkaloids are known to be toxic in humans, particularly to the liver. When choosing butterbur, make sure the product is labeled PA-free.

The amount of alkaloids in butterbur root is minimal, less than 0.01% concentration. Most butterbur treatment regimens recommend taking the supplement for a maximum of for to six months. If migraine frequency increases, it is safe to take again for another 4-6 months, but at least a month needs to separate each course of treatment.

Aging and Migraines

Monday, November 16th, 2009

Aging is a fact of life. Getting older means increasing frailty and susceptibility to illness, but it can also be a boon to migraineurs (people who experience migraine headaches). Only 2-10% of the elderly population experiences migraines (as opposed to up to 28% of adults under 65), and elderly women are still more likely to have them than their male counterparts.

Migraines can happen at any age, but they peak around age 40. The frequency of migraine attacks after 40 decreases for most people. Many migraineurs who have suffered with this condition for years experience a reduction in the frequency and severity of attacks after age 55.

About two thirds of migraineurs stop having attacks altogether by age 65. Patients over 65 who still have migraines report drastically decreased severity, duration, and frequency in their attacks. They are also less likely to experience the gastrointestinal upset that accompanies migraine in younger people.

The downside to all this good news is that adults over 65 who suffer from migraines are more likely than younger patients to experience disability because of their affliction. Many physicians are uncomfortable with treating senior citizens for migraines because therapeutic methods used on younger people are often not tested for safety in an older patient.

Additional conditions and the medications used to treat them complicate the problem. Seniors are more likely to be on one or more prescription drugs and each new medication increases the risk of adverse drug reactions. This possibility makes some doctors reluctant to offer senior migraineurs pharmaceutical assistance.

The onset of migraines after age 50 is very rare and should be investigated with a doctor to rule out the possibility of secondary causes. Late onset does not rule out migraine (only one third of senior headaches are due to secondary conditions) but it makes it less likely.

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